Regulation of MEIS1 by distal enhancer elements in acute leukemia
نویسندگان
چکیده
منابع مشابه
Regulation of the PU.1 gene by distal elements.
The transcription factor PU.1 (also known as Spi-1) plays a critical role in the development of the myeloid lineages, and myeloid cells derived from PU.1(-/-) animals are blocked at the earliest stage of myeloid differentiation. Expression of the PU.1 gene is tightly regulated during normal hematopoietic development, and dysregulation of PU.1 expression can lead to erythroleukemia. However, rel...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2013
ISSN: 0887-6924,1476-5551
DOI: 10.1038/leu.2013.260